解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::We describe a polymorphism in the bovine gene PTHG which can be readily typed by PCR assay. The polymorphism is codominantly inherited and the allele frequencies appear characteristic of Bo indicus and B. taurus cattle. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00323.x
更新日期:1993-08-01 00:00:00
abstract::A synthetic oligodeoxyribonucleotide probe (OAT36) comprising nine repeats of 5'GACA 3' and several enzymes were used to analyse cow, (Bos taurus) and buffalo (Bubalus bubalis) genomes and a number of monomorphic loci were detected in both the species. Different animals from the same species showed an almost 'similar'...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00288.x
更新日期:1993-06-01 00:00:00
abstract::Linkage between the amylase-1 (Am-1) locus and a quantitative trait locus influencing fat content in milk was studied in offspring from heterozygous sires of the Swedish Red and White dairy breed. The effect on bull breeding values for fat content was estimated as interactions between sire and paternal Am-1 allele usi...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00248.x
更新日期:1993-04-01 00:00:00
abstract::The bovine major histocompatibility complex differs from that of other species in that it has a second group of class II genes that are separated from the classical class I/class II complex by 15 to 20 centimorgans. Two class II bovine genes, BoLA-DYA and BoLA-DIB, seem to be unique based on sequence analysis. To inve...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00917.x
更新日期:1993-02-01 00:00:00
abstract::Analysis of elution profiles of enzymatic and CNBr digests of kappa-caseins C and E, and sequencing of most relevant peptides allowed the chemical characterization of both genetic variants. They differ from their B and A allelic counterparts by a single substitution, His97/Arg and Gly155/Ser, respectively. Electrophor...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1993.tb00915.x
更新日期:1993-02-01 00:00:00
abstract::cDNAs encoding porcine beta-lactoglobulin were isolated and sequenced. The porcine beta-lactoglobulin cDNA is 768bp in length and encodes a pre-protein of 178 amino acids. One additional cDNA clone was found to encode an additional amino acid (lysine) in the mature protein. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00139.x
更新日期:1992-01-01 00:00:00
abstract::A canine blood group antigen, QN, which was detected by a naturally occurring alloantibody in the antiglobulin test, was shown to be antigenically related to the human A and cattle J antigens by absorption experiments. Family studies supported a dominant mode of inheritance with the gene controlling the production of ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00153.x
更新日期:1992-01-01 00:00:00
abstract::Porcine lipoprotein lipase (LPL) cDNA has been cloned and sequenced. The deduced amino acid sequence shows a high degree of identity to LPL from other species, and contains the Ser/His/Asp triade characteristic of serine proteases and esterases. A repetitive element is present in the 3'-untranslated region of the cDNA...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00170.x
更新日期:1992-01-01 00:00:00
abstract::Two cDNA probes for the porcine calcium release channel gene (CRC) were used in restriction fragment length polymorphism (RFLP) analysis in an attempt to develop genetic markers linked to the malignant hyperthermia (stress susceptibility) gene (HAL). Three TaqI RFLPs, denoted CRC1-CRC3, each composed of two alleles, w...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00138.x
更新日期:1992-01-01 00:00:00
abstract::In order to obtain monoclonal alloantibodies against bovine blood group antigens, lymph node cells from calves immunized with bovine red blood cells (RBC) were fused with either murine NSO/1 myeloma cells or a HAT sensitive murine x bovine heterohybridoma cell line. Both fusion partners resulted in heterohybridoma cel...
journal_title:Animal genetics
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::We have used the polymerase chain reaction (PCR) to amplify exon VII of the bovine beta-casein gene. The mutations responsible for the B variant were identified by direct sequencing of the amplification products. A bidirectional allele-specific PCR method (BAS-PCR) has been developed using oligonucleotides overlapping...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00180.x
更新日期:1992-01-01 00:00:00
abstract::A genetic disease observed in certain Quarter horses is hyperkalaemic periodic paralysis (HYPP). This disease causes attacks of paralysis which can be induced by ingestion of potassium. Recent studies have shown that HYPP in humans is due to single base changes within the adult skeletal muscle sodium channel gene. A l...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb00136.x
更新日期:1992-01-01 00:00:00
abstract::Swine genomic DNA segments containing repetitive sequences were isolated from a porcine genomic library using genomic DNA as a probe. Three fragments containing the repetitive sequences from two of the primary phage clones were subcloned for sequence analysis, which revealed six new PRE-1 repetitive families other tha...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1992.tb02164.x
更新日期:1992-01-01 00:00:00
abstract::By means of a new antiserum, Mm, the Mae phenotype can be shown to be controlled by the Maem allele, the Mef phenotype by either the original Mef or a new Mefm allele, and the Mbe(f) phenotype by the Mbe(f)m allele. The complexity of the porcine M system is now extended to 13 internationally recognized blood group fac...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1991.tb00661.x
更新日期:1991-01-01 00:00:00
abstract::Cows carrying unrelated transferred embryos (ET) produced anti-leucocyte serum antibodies (aLA) more often than cows carrying their own embryos. Cows carrying the ET showed a higher frequency of cytotoxic reactions against leucocytes from 40-60 randomly chosen cows than individuals carrying their own embryos. The perc...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1991.tb00674.x
更新日期:1991-01-01 00:00:00
abstract::Ten alloantisera defining five major histocompatibility complex (MHC) class II specificities of the bovine lymphocyte antigen (BoLA) complex were produced and characterized. Eight antisera defining four of the specificities were generated by immunizing cattle with class I compatible-class II incompatible lymphocytes. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1991.tb00701.x
更新日期:1991-01-01 00:00:00
abstract::The C3 polymorphism of equine serum or plasma revealed by agarose gel electrophoresis can be diagnosed with protein stain following acid protein fixation. In addition to the three alleles previously described (C31, C32, C33), a fourth allele (C34) was found. Population data for 25 domestic breeds and Equus przewalskii...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1990.tb03210.x
更新日期:1990-01-01 00:00:00
abstract::Animals were identified from two sire lines as being homozygous for the class I bovine lymphocyte antigen (BoLA-A) w23. These animals were also shown to be homozygous for class II antigens (BoLA-D) which, however, differed between the two sire lines. Lymphocytes from these animals were then used either as stimulator c...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1990.tb03218.x
更新日期:1990-01-01 00:00:00
abstract::Two new haemoglobin variants, provisionally named Hb G and Hb H, were found during a survey of 295 Welsh Mountain cross-bred sheep. Both haemoglobins appear to be beta chain variants controlled by genes allelic to those for the common forms Hb A and Hb B. Studies on an anaemic Hb AH and an Hb AG type sheep showed that...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1990.tb03215.x
更新日期:1990-01-01 00:00:00
abstract::Restriction site heteroplasmy involving the enzymes NcoI and XbaI was detected in the mitochondrial DNAs of two individuals of the marine fish Sciaenops ocellatus. This represents only the sixth documented example of mitochondrial DNA restriction site heteroplasmy in animals. Two heteroplasmic individuals were found i...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1990.tb03241.x
更新日期:1990-01-01 00:00:00
abstract::A study of erythrocyte superoxide dismutase in Cervus dama, Cervus elaphus, Cervus nippon and Cervus elaphus x Cervus nippon hybrids has revealed a polymorphism of this enzyme system in Cervus elaphus as well as in the hybrid population. Genetic analysis suggests that this enzyme system is controlled by one gene locus...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1990.tb01983.x
更新日期:1990-01-01 00:00:00
abstract::Genomic DNAs from animals representing six breeds of cattle (Angus, Brahman, Hereford, Holstein, Jersey and Texas Longhorn) were screened with cloned gene probes in a search for restriction fragment length polymorphisms (RFLPs). Eleven RFLPs were identified using seven different probes: growth hormone, prolactin, oste...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1989.tb00866.x
更新日期:1989-01-01 00:00:00
abstract::This study presents evidence that sheep haemopexin phenotypes are genetically controlled by three alleles, HpxA, HpxB1 and HpxB2, of a single autosomal locus. Frequencies of two alleles, HpxA and HpxB (HpxB encompasses two isoalleles, HpxB1 and HpxB2), were studied in eight sheep breeds in Czechoslovakia. The frequenc...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1989.tb00856.x
更新日期:1989-01-01 00:00:00
abstract::Described is an alternative procedure for the phenotyping of pig alpha 1B-glycoprotein (PO2) and haemopexin. The procedure is based on the separation of serum samples by horizontal polyacrylamide gel electrophoresis, passive blotting onto a nitrocellulose (NC) sheet, and immunochemical detection using a mixture of a p...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1989.tb00870.x
更新日期:1989-01-01 00:00:00
abstract::Diagnostic criteria should be carefully defined and described in disease association studies to allow (1) comparison among studies from different laboratories evaluating the same disease, (2) critical evaluation of selection procedures of patients, and (3) to strengthen genuine associations with any genetic marker sys...
journal_title:Animal genetics
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2052.1988.tb00832.x
更新日期:1988-01-01 00:00:00
abstract::A new variant of glucose phosphate isomerase (GPI), also known as phosphohexose isomerase (PHI), was detected in a primitive pig population. ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1988.tb00790.x
更新日期:1988-01-01 00:00:00
abstract::Blood samples of llamas and alpacas were typed using haemolytic, electrophoretic and isoelectric focusing procedures to assay polymorphism at 13 loci. Blood group variation was assessed using six antibody specificities produced by allo- and heteroimmunizations. Two red cell factors (A and B) behave as autosomal, codom...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1988.tb00815.x
更新日期:1988-01-01 00:00:00
abstract::Monoclonal antibodies specific for equine T lymphocyte subpopulations were produced and procedures for the continuous culture of equine lymphocytes were developed. These reagents and procedures were used to analyse the appearance, maturation and functions of T lymphocytes in normal horses and in T lymphocyte deficient...
journal_title:Animal genetics
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2052.1988.tb00825.x
更新日期:1988-01-01 00:00:00
abstract::A cDNA library for porcine skeletal muscle was established in the vector pBR322. The library was screened with an oligonucleotide probe coding for a hexapeptide from glucosephosphate isomerase (Gpi). A positive clone with an insert of about 450 bp and restriction sites for PstI, BamHI and PvuII was isolated. A 362-bp ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00763.x
更新日期:1987-01-01 00:00:00
abstract::The influence of the major histocompatibility (B) complex and sex on the phytohaemagglutinin (PHA) wattle response was studied in 136 segregants (B2/B2, B2/B5 and B5/B5) of a fourth generation cross between inbred lines 6(1) and 15(1). At 6 weeks of age, chickens were injected with 100 micrograms purified PHA-P. Wattl...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00778.x
更新日期:1987-01-01 00:00:00
abstract::Linkage analysis between the genes coding for immunoglobulin heavy-chain allotypes and variants of some serum alpha-protease inhibitors produced lod scores above the significance limit of 3. The maximum likelihood estimate of the recombination fraction (theta) ranged from 0.15 to 0.20. Since this is the second report ...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00779.x
更新日期:1987-01-01 00:00:00
abstract::Plasma samples of 1126 dogs belonging to 21 different European breeds were analysed by two-dimensional agarose gel (pH 5.4 or pH 8.6)--horizontal polyacrylamide gel (pH 9.0) electrophoresis, followed by general-protein staining of gels. Genetic polymorphism was detected for five as yet unidentified proteins designated...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00773.x
更新日期:1987-01-01 00:00:00
abstract::The expression of haemoglobin (Hb) has been studied in 260 Norwegian Dairy goats by the Immobiline technique at pH ranges 6.7-7.7, 6.9-7.6 and 6.9-7.5. The majority of goats exhibited two- or four-band patterns. In two-band types the average ratio between the anodal and cathodal band was 74:26. PAGE with 8M urea disti...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00762.x
更新日期:1987-01-01 00:00:00
abstract::DNA samples obtained from sheep homozygous for HbA, for HbB and heterozygous were subjected to Southern blot analysis using a goat beta F and a rabbit beta 1-globin gene as probes. Sheep homozygous for HbA show a different restriction pattern from that of sheep homozygous for HbB with each of the used endonucleases. T...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1987.tb00764.x
更新日期:1987-01-01 00:00:00
abstract::The Third International Workshop on Lymphocyte Alloantigens of the Horse was held on 25-27 April 1984 in Kennett Square, Pennsylvania. Twelve laboratories from five countries participated. The principal purpose of this Workshop was to determine the phenotypic and gene frequencies of the 10 equine lymphocyte antigens (...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1986.tb00730.x
更新日期:1986-01-01 00:00:00
abstract::The distribution of biochemical genetic variants was examined among eight inbred strains of mice, which served as contributors to a heterogeneous stock of mice (HS), and in short-sleep (SS) and long-sleep (LS) mice, selectively bred from the HS stock for differential ethanol sensitivity. Fifteen loci for enzymes of al...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1986.tb03195.x
更新日期:1986-01-01 00:00:00
abstract::Israeli Holstein-Friesian dairy bulls were screened for restriction fragment length polymorphisms by hybridizing cloned DNA probes for bovine growth hormone, for chymosin, and for rat muscle beta-actin to restriction endonuclease-digested DNA immobilized on nitrocellulose filters. The population proved to be polymorph...
journal_title:Animal genetics
pub_type: 杂志文章
doi:10.1111/j.1365-2052.1986.tb03185.x
更新日期:1986-01-01 00:00:00